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わかさの秘密トップ > 成分情報 > ゼアキサンチン > ゼアキサンチン 参考文献

作成日 2012年09月13日
更新日 2014年06月17日

ゼアキサンチン

zeaxanthin

ゼアキサンチンは、緑黄色野菜に多く含まれているカロテノイドの一種です。
強力な抗酸化作用を持ち、人間の体内ではルテインとともに黄斑部に存在しています。
黄斑変性症や白内障の予防に対する効果が期待されています。

参考文献

・Bian Q, Gao S, Zhou J, Qin J, Taylor A, Johnson EJ, Tang G, Sparrow JR, Gierhart D, Shang F. “Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells.” Free Radic Biol Med.

・Tanito M, Obana A, Gohto Y, Okazaki S, Gellermann W, Ohira A. 2012 “Macular pigment density changes in Japanese individuals supplemented with lutein or zeaxanthin:quantification via resonance Raman spectrophotometry and autofluorescence imaging.” Jpn J Ophthalmol. 2012

・Nolan JM, Akkali MC, Loughman J, Howard AN, Beatty S. 2012 “Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment.” Exp Eye Res. May 28;101C: 9-15.

・Graydon R, Hogg RE, Chakravarthy U, Young IS, Woodside JV. 2012 “The effect of lutein- and zeaxanthin-rich foods v. supplements on macular pigment level and serological markers of endothelial activation, inflammation and oxidation:pilot studies in healthy volunteers.” Br J Nutr. 2012 Feb 7:1-9.

・Gao S, Qin T, Liu Z, Caceres MA, Ronchi CF, Chen CY, Yeum KJ, Taylor A, Blumberg JB, Liu Y, Shang F. 2011 “Lutein and zeaxanthin supplementation reduces H2O2-induced oxidative damage in human lens epithelial cells.” Mol Vis. 2011;17:3180-90.

・Lidebjer C, Leanderson P, Ernerudh J, Jonasson L. 2007 “Low plasma levels of oxygenated carotenoids in patients with coronary artery disease.” Nutr Metab Cardiovasc Dis. 2007 Jul;17(6):448-56.

・Ribaya-Mercado JD, Blumberg JB. 2004 “Lutein and zeaxanthin and their potential roles in disease prevention.” J Am Coll Nutr. 2004 Dec;23(6 Suppl):567S-587S.

・Stahl W. 2005 “Macular carotenoids: lutein and zeaxanthin.” Dev Ophthalmol. 2005;38:70-88.

・Astner S, Wu A, Chen J, Philips N, Rius-Diaz F, Parrado C, Mihm MC, Goukassian DA, Pathak MA, González S. 2007 “Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice.” Skin Pharmacol Physiol. 2007;20(6):283-91.

・Palombo P, Fabrizi G, Ruocco V, Ruocco E, Fluhr J, Roberts R, Morganti P. 2007 “Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study.” Skin Pharmacol Physiol. 2007;20(4):199-210.

・Brazionis L, Rowley K, Itsiopoulos C, O'Dea K. 2009 “Plasma carotenoids and diabetic retinopathy.” Br J Nutr. 2009 Jan;101(2):270-7..

・Kowluru RA, Menon B, Gierhart DL 2008 “Beneficial effect of zeaxanthin on retinal metabolic abnormalities in diabetic rats.” Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1645-51.

・Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, et al. 1994 “Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group.” JAMA. 1994 Nov 9;272(18):1413-20.

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