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わかさの秘密トップ > 成分情報 > DHA(ドコサヘキサエン酸) > DHA(ドコサヘキサエン酸) 参考文献

作成日 2012年09月13日
更新日 2014年05月01日

DHA(ドコサヘキサエン酸)

Docosahexaenoic acid

DHA(ドコサヘキサエン酸)は青魚に多く含まれている多価不飽和脂肪酸で、体内ではEPA(エイコサペンタエン酸)からつくられ、脳や神経組織の機能を高める働きがあります。脳は脳内に入れる成分と入れない成分を選別しますが、DHAは脳内に入ることができ、神経細胞を活性化させ記憶力や学習能力を向上させます。

参考文献

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・Wu JH, Lemaitre RN, King IB, Song X, Sacks FM, Rimm EB, Heckbert SR, Siscovick DS, Mozaffarian D. 2012 “Association of plasma phospholipid long-chain ω-3 fatty acids with incident atrial fibrillation in older adults: the cardiovascular health study.” Circulation. 2012 Mar 6;125(9):1084-93.
 
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・Martin CR, Blanco PG, Keach JC, Petz JL, Zaman MM, Bhaskar KR, Cluette-Brown JE, Gautam S, Sheth S, Afdhal NH, Lindor KD, Freedman SD. 2012 “The safety and efficacy of oral docosahexaenoic acid supplementation for the treatment of primary sclerosing cholangitis - a pilot study.” Aliment Pharmacol Ther. 2012 Jan;35(2):255-65.

・Bernstein AM, Ding EL, Willett WC, Rimm EB. 2012 “A meta-analysis shows that docosahexaenoic acid from algal oil reduces serum triglycerides and increases HDL-cholesterol and LDL-cholesterol in persons without coronary heart disease.” J Nutr. 2012 Jan;142(1):99-104.

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・Martinez-Micaelo N, Gonzalez-Abuin N, Terra X, Richart C, Ardevol A, Pinent M, Blay M. 2012 “Omega-3 docosahexaenoic acid and procyanidins inhibit cyclo-oxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation.” Biochem J. 2012 Jan 15;441(2):653-63.

・Sarris J, Mischoulon D, Schweitzer I. 2012 “Omega-3 for bipolar disorder: meta-analyses of use in mania and bipolar depression.” J Clin Psychiatry. 2012 Jan;73(1):81-6.

・Moriguchi T, Loewke J, Garrison M, Catalan JN, Salem N Jr. 2001 “Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum.” J Lipid Res. 2001 Mar;42(3):419-27.

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・Hibbeln JR. 2002 “Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis.” J Affect Disord. 2002 May;69(1-3):15-29.

・Hamazaki T, Sawazaki S, Itomura M, Asaoka E, Nagao Y, Nishimura N, Yazawa K, Kuwamori T, Kobayashi M. 1996 “The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study.” J Clin Invest. 1996 Feb 15;97(4):1129-33.

・Hoffman DR, Birch EE, Birch DG, Uauy R, Castañeda YS, Lapus MG, Wheaton DH. 2000 “Impact of early dietary intake and blood lipid composition of long-chain polyunsaturated fatty acids on later visual development.” J Pediatr Gastroenterol Nutr. 2000 Nov;31(5):540-53.

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